Courtesy of Baseball HQ:
"We could debate Joe Mauer (C, MIN) in Round 1 forever. He's worth it, but what a huge risk building your team on a catcher. With Pittsburgh's unsettled catching and first base situations, Ryan Doumit (C, PIT) seems a great buy-low candidate. He possesses all the skills and is now healthy. With an ADP of 205, you should be able to nab him about twenty spots earlier and get solid value. Mike Napoli (C, LAA) again seems reasonably priced behind light-hitting Jeff Mathis (C, LA) and the DH opportunities potentially available for the Angels. In the end game, Nick Hundley (C, SD) and John Buck (C, TOR) seem to feature the most profit potential."
I disagree on the adage "You can't win your league in the first few rounds, but you can lose it." I'd take Mauer in the 2nd half of the 1st round, but may begin to adjust to his ADP and hope to get him coming back in the 2nd.